Institute of Pharmaceutical Sciences

OVERVIEW

The Institute of Pharmaceutical Sciences was created on October 29, 1998 during the 1125th UP Board of Regents (BOR) meeting. The IPS envisions itself to become a recognized and relevant institution in the pharmaceutical sciences by providing the facilities, pertinent expertise and comprehensive services, including human resource development to help ensure the provision of safe, effective and quality drugs for the nation.

VISION

The Institute of Pharmaceutical Sciences shall continually strive to become a recognized and relevant institution in the pharmaceutical sciences by providing facilities, pertinent expertise and comprehensive services, including human resource development, to help ensure the provision of safe, effective and quality drugs and pharmaceutical preparations for the nation with due regard to public health impact and safety.

MISSION

To address the research and technical needs of various sectors and stakeholders in the study, provision and utilization of safe, cost-effective and efficacious indigenous and synthetic pharmaceutical preparations.

RESEARCH AGENDA

In order to meet its mission, the IPS shall conduct researches on the following three major areas:

  1. Drug Development - This area aims to come up with cheaper but quality drug alternatives and cost effective pharmaceutical preparations including cosmetic products. Research studies covered in this area include: drug discovery and development, cosmetics product development and efficacy testing, product pre formulation and/or formulation, stability studies, pre-clinical and clinical testing of pharmaceutical formulations.
  2. Pharmacy Practice - Researches in this field are conducted to improve the practice of pharmacy in the country. Scope of this research area includes: rational drug use, clinical pharmacy services and practice, pharmacy education, public health pharmacy, patient safety, outcomes research and pharmaco-economics studies, pharmaco-epidemiology and policy review and formulation.
  3. Bioavailability/Bioequivalence Testing - Timely and relevant researches to validate both in vitro and in vivo studies on dissolution-bioavailability will be performed in this area. Local as well as multinational drug companies are expected to benefit from this endeavor. Research studies include in vitro dissolution testing, in vitro-in vivo correlation studies and BioA/BioE studies.

SERVICES

The Institute of Pharmaceutical Sciences offers the following services to students and non-students:

TYPE OF ANALYSIS

REQUIREMENTS

LEAD TIME

RATE, P

NATURAL PRODUCTS

Extraction (Maceration)

Pulverized sample (at least 250 g), procedure (type of solvent to be used, weight-solvent ratio, etc.)

10 working days (For special cases, i.e. longer soaking time, lead time will depend on the analyst)

500/250 g sample

Phytochemical screening (qualitative)

Plant extract (at least 2 g for crude extract and 60 mL for extracts in their mother solvent)

 

10 working days

700

Total flavonoids

Plant extract (at least 1 g of crude extract or depending on the concentration of the sample)

 

10 working days

2,000

Total phenolics

Plant extract (at least 1 g of crude extract or depending on the concentration of the sample)

 

10 working days

1,500

Total tannins

Plant extract (at least 1 g of crude extract or depending on the concentration of the sample)

 

10 working days

3,500

Isolation of tannins

Plant extract (at least 1 g of crude extract or depending on the concentration of the sample)

 

10 working days

1,200

Thin layer chromatography

Plant extract (at least 1 g of crude extract), procedure (solvent system, visualization technique, etc.)

 

10 working days

500

DPPH radical scavenging assay

Plant extracts (at least 1 g), concentrations to be used

10 working days

1500/5 conc.

FRAP assay

Plant extracts (at least 1 g), concentrations to be used

 

10 working days

1300/5 conc.

PHARMACEUTICAL PRODUCTS

Potency assay

Samples (tablet/capsules: 40 pcs., ampoules/vials/suspensions: 4 pcs.), procedure, reference/working standard, certificate of analysis (standard and finished product)

1-1.5 months

4,200/sample

RESEARCHES

These are the research projects the Institute have accomplished and are currently doing (from 2014 to present):

 

Title

Year

Funding Agency

1

Screening for Antioxidant and Antimicrobial Activities of Some Plants for Potential Use as Preservatives

 

2013-2014

NIH

2

Alternative and Sustainable Resources of Natural Preservatives

 

2014-2015

NRCP

3

Extraction and Purification of Pectin from Fruit Peel Waste of Selected Philippine Fruits

 

2014-2015

NRCP

4

Anti-inflammatory and Wound Healing Property of Coconut Germ Oil

 

2014-2015

NIH

5

In-Vitro Equivalence Testing of Selected Generic Essential Medicines Eligible for BCS-Based Biowaiver

 

2014-2016

PCHRD-DOST

6

Antioxidant and Antimicrobial Property of Caesalpinia pulcherrima (L.) Swartz

 

2015-2016

IPS

7

Extraction, Purification, and Evaluation of Selected Fruit Waste-Derived Starch as Pharmaceutical Excipients

 

2016-2017

PITAHC

8

Extraction and Bioassay Evaluation of Selected Philippine Plants for Diabetes, Hyperlipidemia, and Hypertension

 

2016-2018

NRCP

9

Evaluation of Safety and Efficacy of Makabuhay Thin Ointment against Head Lice

 

2016-2017

PITAHC

10

Extraction and Physicochemical Characterization of Chitin from Molluscan Shell Wastes

 

2016-2017

IPS

11

Development and Evaluation of Anti-Inflammatory and Wound-Healing Gel Preparation containing Cocos nucifera Germ Oil

 

2016-2017

NIH

12

Antimicrobial Activity of Calcium Hydroxide, Chlorhexidine, C. pulcherrima and Their Combination in E. faecalis and C. albicans

 

2016-2017

NIH

13

Evaluation of safety and efficacy of Siling labuyo liniment for the management of Osteoarthritis

 

2016-2017

PITAHC

14

An Evaluation of the Safety and Efficacy of Community-produced Senna alata (Akapulko) 50% Thin Ointment Compared to Clottimazole 1% Cream in the Treatment of Pityriasis Versicolor: An assessor-blinded, randomized controlled trial

2016-2017

PITAHC

STAFF

Erna C. Arollado, RPh., MSc., PhD.
Director

Ana Rose V. Palmes
Administrative Officer

Richelle Ann M. Manalo, RCh.
University Researcher

Gerwin Louis T. Dela Torre, RPh.
University Research Associate I

Joriza Mae M. Pellazar, RPh.
Research Associate

Mae Pauline F. Siocson
Research Assistant

Shaina Mara M. Salvador
Research Assistant

Patrick Jacob L. Liwag, RCh.
Research Assistant

Angelica Louise D. De Guzman, RCh.
Research Assistant

Clarisse Julian A. Pangilinan, RCh.
Research Assistant

Romeo-Luis F. Ramirez
Research Assistant

CONTACT INFORMATION

Tel. No: (02) 577-2001/0917 838 6327
E-Mail Address: ips_nih@yahoo.com
Address: Institute of Pharmaceutical Sciences
Room 212, National Institutes of Health
University of the Philippines Manila, P. Gil St., Ermita, Manila